منابع مشابه
Hexanucleotide frequency database
A database of the frequency of hexanucleotides observed in different categories of the EMBL public domain sequence database is described. A wide range of procedures in molecular biology could benefit from knowledge of the real, as opposed to the projected, frequency of oligonucleotides in the target genomic DNA or mRNA population. These include the design of primers and probes, the detection of...
متن کاملALFRED: a Web-accessible allele frequency database.
We present a Web-accessible database (ALFRED) that allows public access to gene frequency data for a diverse set of population samples and genetic systems. The data in ALFRED are modeled based on the experience and needs of a single laboratory, but with the expectation that the database will meet the needs of a much broader scientific community that needs population-specific gene frequency esti...
متن کاملALFRED: the ALelle FREquency Database. Update
Elaboration of ALFRED (http://alfred.med.yale.edu) is being continued in two directions. One of which is developing tools for efficiently annotating the entries and checking the integrity of the data already in the database while the other is to increase the quantity and accessibility of data. Information contained in ALFRED such as, polymorphic sites, number of populations and frequency tables...
متن کاملALFRED: An allele frequency database for anthropology.
The deluge of data from the human genome project (HGP) presents new opportunities for molecular anthropologists to study human variation through the promise of vast numbers of new polymorphisms (e.g., single nucleotide polymorphisms or SNPs). Collecting the resulting data into a single, easily accessible resource will be important to facilitate this research. We created a prototype Web-accessib...
متن کاملFrequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
BACKGROUND We aimed to accurately estimate the frequency of a hexanucleotide repeat expansion in C9orf72 that has been associated with a large proportion of cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). METHODS We screened 4448 patients diagnosed with ALS (El Escorial criteria) and 1425 patients with FTD (Lund-Manchester criteria) from 17 regions worldwide fo...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 1997
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/13.1.107